@article {2021|2155,
	title = {Modeling Perturbations in Protein Filaments at the Micro and Meso Scale Using NAMD and PTools/Heligeom},
	journal = {Bio-protocol},
	volume = {11},
	year = {2021},
	pages = {e4097},
	abstract = {<p>Protein filaments are dynamic entities that respond to external stimuli by slightly or substantially modifying the internal binding geometries between successive protomers. This results in overall changes in the filament architecture, which are difficult to model due to the helical character of the system. Here, we describe how distortions in RecA nucleofilaments and their consequences on the filament-DNA and bound DNA-DNA interactions at different stages of the homologous recombination process can be modeled using the PTools/Heligeom software and subsequent molecular dynamics simulation with NAMD. Modeling methods dealing with helical macromolecular objects typically rely on symmetric assemblies and take advantage of known symmetry descriptors. Other methods dealing with single objects, such as MMTK or VMD, do not integrate the specificities of regular assemblies. By basing the model building on binding geometries at the protomer-protomer level, PTools/Heligeom frees the building process from a priori knowledge of the system topology and enables irregular architectures and symmetry disruption to be accounted for. doi: 10.21769/BioProtoc.4097</p>
},
	doi = {10.21769/BioProtoc.4097},
	url = {www.bioprotocol.org/e4097},
	author = {Boyer, B. and Laurent, B. and Robert, C. H. and Prevost, C.}
}
@article {2010|1516,
	title = {{M}ulti-resolution approach for interactively locating functionally linked ion binding sites by steering small molecules into electrostatic potential maps using a haptic device},
	journal = {Pac. Symp. Biocomput.},
	year = {2010},
	pages = {205{\textendash}215},
	author = {Delalande, O. and Nicolas F{\'e}rey and Laurent, B. and Gueroult, M. and Hartmann, B. and Marc Baaden}
}
