@article {2009|1831, title = {Key role of proximal water in regulating thermostable proteins}, journal = {J. Phys. Chem. B}, volume = {113}, number = {1}, year = {2009}, month = {jan}, pages = {131{\textendash}7}, abstract = {Three homologous proteins with mesophilic, thermophilic and hyperthermophilic character have been studied via molecular dynamics simulations at four different temperatures in order to investigate how water controls thermostability. The water-exposed surface of the protein is shown to increase with the degree of thermophilicity, and the role of water in enhancing the protein internal flexibility and structural robustness is elucidated. The presence of water-water hydrogen bond clusters enveloping the macromolecule is shown to correlate with thermal robustness when going from the mesophilic to the hyperthermophilic variants. Our analysis indicates that essential contributions to thermostability stem from protein-water surface effects whereas the protein internal packing plays a minor role.}, doi = {10.1021/jp805199c}, author = {Sterpone, Fabio and Bertonati, Claudia and Briganti, Giuseppe and Melchionna, Simone} } @article {2009|1863, title = {Kinetic and thermodynamic DNA elasticity at micro- and mesoscopic scales}, journal = {J. Phys. Chem. B}, volume = {113}, year = {2009}, pages = {2077{\textendash}2089}, author = {Alexey K Mazur} } @article {2008|1515, title = {KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007}, journal = {Nucleic Acids Res.}, volume = {36}, number = {Sp. Iss. SI}, year = {2008}, month = {jan}, pages = {D314-D319}, keywords = {knottin}, author = {Gracy, Jerome and Le-Nguyen, Dung and Gelly, Jean-Christophe and Kaas, Quentin and Heitz, Annie and Chiche, Laurent} } @article {2004|1513, title = {The KNOTTIN website and database: a new information system dedicated to the knottin scaffold}, journal = {Nucleic Acids Res.}, volume = {32}, number = {Sp. Iss. SI}, year = {2004}, month = {jan}, pages = {D156-D159}, author = {Gelly, JC and Gracy, J and Kaas, Q and Le-Nguyen, D and Heitz, A and Chiche, L} } @article {1992|1596, title = {Kinetics of pore-mediated release of marker molecules from liposomes or cells}, journal = {Biophys. Chem.}, volume = {42}, number = {3}, year = {1992}, month = {apr}, pages = {291{\textendash}296}, author = {Schwarz, G and Charles H. Robert} } @article {1983, title = {Kinetics of glucose accumulation during depolimerization of polysaccharides by enzymes with different mechanisms of action}, journal = {Mol. Biol.}, volume = {17}, year = {1983}, pages = {101{\textendash}111}, author = {Alexey K Mazur and L. A. Elyakova} }