AlphaFold & Co

On the cluster, you can find different software to make structure prediction from primary sequence.

The main one is Alphafold and it's derivatives, all based on Multiple Sequence Alignment (MSA). Others are based on a Protein Language Model (PLM) which don't require any MSA or co-evolution data.

Software	Version Installed	Method	Multimer mode	Documentation	Github
Alphafold	2.3.1	MSA	yes	Wiki	Link
Colabfold	1.5.2	MSA	yes	Wiki	Link
Omegafold	1.1.0	PLM	no	Wiki	Link
ESMFold	1.0.3	PLM	yes	Wiki	Link

CASP14 Example

Here a result of T1050 779 residus protein, a CASP14 target (CASP14 results).

Troubleshooting

In case of trouble, you can contact me at : hubert.santuz[at]ibpc.fr