Molecular Graphics: Bridging Structural Biologists and Computer Scientists.

TitleMolecular Graphics: Bridging Structural Biologists and Computer Scientists.
Publication TypeJournal Article
Year of Publication2019
AuthorsMartinez X, Krone M, Alharbi N, Rose AS, Laramee RS, O'Donoghue S, Baaden M, Chavent M
JournalStructure
Volume27
Issue11
Pagination1617-1623
Date Published2019 11 05
ISSN1878-4186
Abstract

Visualization of molecular structures is one of the most common tasks carried out by structural biologists, typically using software, such as Chimera, COOT, PyMOL, or VMD. In this Perspective article, we outline how past developments in computer graphics and data visualization have expanded the understanding of biomolecular function, and we summarize recent advances that promise to further transform structural biology. We also highlight how progress in molecular graphics has been impeded by communication barriers between two communities: the computer scientists driving these advances, and the structural and computational biologists who stand to benefit. By pointing to canonical papers and explaining technical progress underlying new graphical developments in simple terms, we aim to improve communication between these communities; this, in turn, would help shape future developments in molecular graphics.

DOI10.1016/j.str.2019.09.001
Alternate JournalStructure
Citation Key2019|2079
PubMed ID31564470